INTS4-ALG8 Fusion FISH Probe
The INTS4-ALG8 Fusion FISH Probe is used to confirm a fusion of the INTS4 and ALG8 genes. The fusion of the INTS4 and ALG8 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| INTS4-ALG8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-RERE | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-REOR | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-REGO | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-REGR | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-REAQ | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-ORRE | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-OROR | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-ORGO | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-ORAQ | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-GORE | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-GOOR | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-GOGO | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-GOGR | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-GOAQ | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-GRRE | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-GROR | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-GRGO | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-GRGR | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-GRAQ | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-AQRE | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-AQOR | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-AQGO | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-AQGR | 20 (40 μL) | 200 μL |
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| INTS4-ALG8-20-AQAQ | 20 (40 μL) | 200 μL |
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ALG8 Gene Summary
This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation of proteins. Mutations in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ih). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: ALG8, Alpha-1,3-glucosyltransferase
Chromosome: CHR11: 77811987 -77850699
Locus: 11q14.1
INTS4 Gene Summary
INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Name: Integrator Complex Subunit 4
Chromosome: CHR11: 77589765 -77705717
Locus: 11q14.1
Gene Diseases
The INTS4 ALG8 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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