ILF3-DENND2D Fusion FISH Probe
The ILF3-DENND2D Fusion FISH Probe is used to confirm a fusion of the ILF3 and DENND2D genes. The fusion of the ILF3 and DENND2D genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ILF3-DENND2D-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-RERE | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-REOR | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-REGO | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-REGR | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-REAQ | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-ORRE | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-OROR | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-ORGO | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-ORAQ | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-GORE | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-GOOR | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-GOGO | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-GOGR | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-GOAQ | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-GRRE | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-GROR | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-GRGO | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-GRGR | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-GRAQ | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-AQRE | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-AQOR | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-AQGO | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-AQGR | 20 (40 μL) | 200 μL |
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| ILF3-DENND2D-20-AQAQ | 20 (40 μL) | 200 μL |
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ILF3 Gene Summary
This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014]
Gene Name: Interleukin Enhancer Binding Factor 3
Chromosome: CHR19: 10764936 -10803095
Locus: 19p13.2
DENND2D Gene Summary
The DENN Domain Containing 2D (DENND2D) gene is located on chr1 :111729800-111743281 at 1p13.3-p13.2.
Gene Name: DENN Domain Containing 2D
Chromosome: CHR1: 111729800 -111743281
Locus: 1p13.3-p13.2
Gene Diseases
The ILF3 DENND2D Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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