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IL1RAPL1-MAGEB10 Fusion FISH Probe

The IL1RAPL1-MAGEB10 Fusion FISH Probe is used to confirm a fusion of the IL1RAPL1 and MAGEB10 genes. The fusion of the IL1RAPL1 and MAGEB10 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
IL1RAPL1-MAGEB10-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-RERE 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-REOR 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-REGO 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-REGR 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-REAQ 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-ORRE 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-OROR 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-ORGO 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-ORAQ 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-GORE 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-GOOR 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-GOGO 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-GOGR 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-GOAQ 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-GRRE 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-GROR 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-GRGO 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-GRGR 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-GRAQ 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-AQRE 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-AQOR 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-AQGO 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-AQGR 20 (40 μL) 200 μL
IL1RAPL1-MAGEB10-20-AQAQ 20 (40 μL) 200 μL

IL1RAPL1 Gene Summary

The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization. [provided by RefSeq, Jul 2017]

Gene Name: Interleukin 1 Receptor Accessory Protein Like 1

Chromosome: CHRX: 28605680 -29974017

Locus: Xp21.3-p21.2

MAGEB10 Gene Summary

This gene encodes a member of the B subfamily of the melanoma associated antigen protein family. The encoded protein is specifically expressed in testis and tumor cells. [provided by RefSeq, Apr 2010]

Gene Name: MAGE Family Member B10

Chromosome: CHRX: 27826106 -27841131

Locus: Xp21.3

Gene Diseases

The IL1RAPL1 MAGEB10 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.