IL1RAPL1-MAGEB10 Fusion FISH Probe
The IL1RAPL1-MAGEB10 Fusion FISH Probe is used to confirm a fusion of the IL1RAPL1 and MAGEB10 genes. The fusion of the IL1RAPL1 and MAGEB10 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
IL1RAPL1-MAGEB10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-RERE | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-REOR | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-REGO | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-REGR | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-REAQ | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-ORRE | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-OROR | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-ORGO | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-ORAQ | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-GORE | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-GOOR | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-GOGO | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-GOGR | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-GOAQ | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-GRRE | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-GROR | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-GRGO | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-GRGR | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-GRAQ | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-AQRE | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-AQOR | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-AQGO | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-AQGR | 20 (40 μL) | 200 μL | ||
IL1RAPL1-MAGEB10-20-AQAQ | 20 (40 μL) | 200 μL |
IL1RAPL1 Gene Summary
The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization. [provided by RefSeq, Jul 2017]
Gene Name: Interleukin 1 Receptor Accessory Protein Like 1
Chromosome: CHRX: 28605680 -29974017
Locus: Xp21.3-p21.2
MAGEB10 Gene Summary
This gene encodes a member of the B subfamily of the melanoma associated antigen protein family. The encoded protein is specifically expressed in testis and tumor cells. [provided by RefSeq, Apr 2010]
Gene Name: MAGE Family Member B10
Chromosome: CHRX: 27826106 -27841131
Locus: Xp21.3
Gene Diseases
The IL1RAPL1 MAGEB10 Fusion has been associated with the following diseases:
Disease Name |
---|
Breast Invasive Carcinoma |
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|