IL13RA1-DOCK11 Fusion FISH Probe
The IL13RA1-DOCK11 Fusion FISH Probe is used to confirm a fusion of the IL13RA1 and DOCK11 genes. The fusion of the IL13RA1 and DOCK11 genes has been associated with Prostate Adenocarcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IL13RA1-DOCK11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-RERE | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-REOR | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-REGO | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-REGR | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-REAQ | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-ORRE | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-OROR | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-ORGO | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-ORAQ | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-GORE | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-GOOR | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-GOGO | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-GOGR | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-GOAQ | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-GRRE | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-GROR | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-GRGO | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-GRGR | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-GRAQ | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-AQRE | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-AQOR | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-AQGO | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-AQGR | 20 (40 μL) | 200 μL |
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| IL13RA1-DOCK11-20-AQAQ | 20 (40 μL) | 200 μL |
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IL13RA1 Gene Summary
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]
Gene Name: Interleukin 13 Receptor Subunit Alpha 1
Chromosome: CHRX: 117861558 -117928496
Locus: Xq24
DOCK11 Gene Summary
The Dedicator Of Cytokinesis 11 (DOCK11) gene is located on chrX :117629871-117820123 at Xq24.
Gene Name: Dedicator Of Cytokinesis 11
Chromosome: CHRX: 117629871 -117820123
Locus: Xq24
Gene Diseases
The IL13RA1 DOCK11 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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