IGSF11-UPK1B Fusion FISH Probe
The IGSF11-UPK1B Fusion FISH Probe is used to confirm a fusion of the IGSF11 and UPK1B genes. The fusion of the IGSF11 and UPK1B genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IGSF11-UPK1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-RERE | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-REOR | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-REGO | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-REGR | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-REAQ | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-ORRE | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-OROR | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-ORGO | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-GORE | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-GOOR | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-GOGO | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-GOGR | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-GRRE | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-GROR | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-GRGO | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-GRGR | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-AQRE | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-AQOR | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-AQGO | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-AQGR | 20 (40 μL) | 200 μL |
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| IGSF11-UPK1B-20-AQAQ | 20 (40 μL) | 200 μL |
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UPK1B Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Uroplakin 1B
Chromosome: CHR3: 118892424 -118924000
Locus: 3q13.32
IGSF11 Gene Summary
IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It shares significant homology with coxsackievirus and adenovirus receptor (CXADR; MIM 602621) and endothelial cell-selective adhesion molecule (ESAM).[supplied by OMIM, Apr 2005]
Gene Name: Immunoglobulin Superfamily Member 11
Chromosome: CHR3: 118619478 -118864898
Locus: 3q13.32
Gene Diseases
The IGSF11 UPK1B Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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