IGFN1-KANK1 Fusion FISH Probe
The IGFN1-KANK1 Fusion FISH Probe is used to confirm a fusion of the IGFN1 and KANK1 genes. The fusion of the IGFN1 and KANK1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IGFN1-KANK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-RERE | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-REOR | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-REGO | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-REGR | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-REAQ | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-ORRE | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-OROR | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-ORGO | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-GORE | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-GOOR | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-GOGO | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-GOGR | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-GRRE | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-GROR | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-GRGO | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-GRGR | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-AQRE | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-AQOR | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-AQGO | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-AQGR | 20 (40 μL) | 200 μL |
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| IGFN1-KANK1-20-AQAQ | 20 (40 μL) | 200 μL |
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KANK1 Gene Summary
The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2014]
Gene Name: KN Motif And Ankyrin Repeat Domains 1
Chromosome: CHR9: 504702 -746103
Locus: 9p24.3
IGFN1 Gene Summary
The Immunoglobulin-like And Fibronectin Type III Domain Containing 1 (IGFN1) gene is located on chr1 :201159952-201198080 at 1q32.1.
Gene Name: Immunoglobulin-like And Fibronectin Type III Domain Containing 1
Chromosome: CHR1: 201159952 -201198080
Locus: 1q32.1
Gene Diseases
The IGFN1 KANK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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