IGFBP5-ARHGEF4 Fusion FISH Probe
The IGFBP5-ARHGEF4 Fusion FISH Probe is used to confirm a fusion of the IGFBP5 and ARHGEF4 genes. The fusion of the IGFBP5 and ARHGEF4 genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IGFBP5-ARHGEF4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-RERE | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-REOR | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-REGO | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-REGR | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-REAQ | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-ORRE | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-OROR | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-ORGO | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-ORAQ | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-GORE | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-GOOR | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-GOGO | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-GOGR | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-GOAQ | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-GRRE | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-GROR | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-GRGO | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-GRGR | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-GRAQ | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-AQRE | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-AQOR | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-AQGO | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-AQGR | 20 (40 μL) | 200 μL |
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| IGFBP5-ARHGEF4-20-AQAQ | 20 (40 μL) | 200 μL |
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IGFBP5 Gene Summary
The Insulin Like Growth Factor Binding Protein 5 (IGFBP5) gene is located on chr2 :217536827-217560272 at 2q35.
Gene Name: Insulin Like Growth Factor Binding Protein 5
Chromosome: CHR2: 217536827 -217560272
Locus: 2q35
ARHGEF4 Gene Summary
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by this gene may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jun 2013]
Gene Name: Rho Guanine Nucleotide Exchange Factor 4
Chromosome: CHR2: 131674223 -131804836
Locus: 2q21.1
Gene Diseases
The IGFBP5 ARHGEF4 Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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