IGF2BP1-BAIAP2 Fusion FISH Probe
The IGF2BP1-BAIAP2 Fusion FISH Probe is used to confirm a fusion of the IGF2BP1 and BAIAP2 genes. The fusion of the IGF2BP1 and BAIAP2 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IGF2BP1-BAIAP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-RERE | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-REOR | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-REGO | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-REGR | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-REAQ | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-ORRE | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-OROR | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-ORGO | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-GORE | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-GOOR | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-GOGO | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-GOGR | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-GRRE | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-GROR | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-GRGO | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-GRGR | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-AQRE | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-AQOR | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-AQGO | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-AQGR | 20 (40 μL) | 200 μL |
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| IGF2BP1-BAIAP2-20-AQAQ | 20 (40 μL) | 200 μL |
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BAIAP2 Gene Summary
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
Gene Name: BAI1 Associated Protein 2
Chromosome: CHR17: 79008946 -79091232
Locus: 17q25.3
IGF2BP1 Gene Summary
This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Name: Insulin Like Growth Factor 2 MRNA Binding Protein 1
Chromosome: CHR17: 47074773 -47133507
Locus: 17q21.32
Gene Diseases
The IGF2BP1 BAIAP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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