IGF2-YY1 Fusion FISH Probe
The IGF2-YY1 Fusion FISH Probe is used to confirm a fusion of the IGF2 and YY1 genes. The fusion of the IGF2 and YY1 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IGF2-YY1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-RERE | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-REOR | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-REGO | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-REGR | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-REAQ | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-ORRE | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-OROR | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-ORGO | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-ORAQ | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-GORE | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-GOOR | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-GOGO | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-GOGR | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-GOAQ | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-GRRE | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-GROR | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-GRGO | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-GRGR | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-GRAQ | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-AQRE | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-AQOR | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-AQGO | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-AQGR | 20 (40 μL) | 200 μL |
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| IGF2-YY1-20-AQAQ | 20 (40 μL) | 200 μL |
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IGF2 Gene Summary
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Name: Insulin Like Growth Factor 2
Chromosome: CHR11: 2150346 -2170833
Locus: 11p15.5
YY1 Gene Summary
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq, Jul 2008]
Gene Name: YY1 Transcription Factor
Chromosome: CHR14: 100705101 -100744804
Locus: 14q32.2
Gene Diseases
The IGF2 YY1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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