IGF2-SNW1 Fusion FISH Probe
The IGF2-SNW1 Fusion FISH Probe is used to confirm a fusion of the IGF2 and SNW1 genes. The fusion of the IGF2 and SNW1 genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IGF2-SNW1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-RERE | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-REOR | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-REGO | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-REGR | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-REAQ | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-ORRE | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-OROR | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-ORGO | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-ORAQ | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-GORE | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-GOOR | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-GOGO | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-GOGR | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-GOAQ | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-GRRE | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-GROR | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-GRGO | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-GRGR | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-GRAQ | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-AQRE | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-AQOR | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-AQGO | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-AQGR | 20 (40 μL) | 200 μL |
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| IGF2-SNW1-20-AQAQ | 20 (40 μL) | 200 μL |
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IGF2 Gene Summary
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Name: Insulin Like Growth Factor 2
Chromosome: CHR11: 2150346 -2170833
Locus: 11p15.5
SNW1 Gene Summary
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Name: SNW Domain Containing 1
Chromosome: CHR14: 78183943 -78227497
Locus: 14q24.3
Gene Diseases
The IGF2 SNW1 Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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