IGF2-EIF2AK2 Fusion FISH Probe
The IGF2-EIF2AK2 Fusion FISH Probe is used to confirm a fusion of the IGF2 and EIF2AK2 genes. The fusion of the IGF2 and EIF2AK2 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IGF2-EIF2AK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-RERE | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-REOR | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-REGO | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-REGR | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-REAQ | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-ORRE | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-OROR | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-ORGO | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-GORE | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-GOOR | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-GOGO | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-GOGR | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-GRRE | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-GROR | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-GRGO | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-GRGR | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-AQRE | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-AQOR | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-AQGO | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-AQGR | 20 (40 μL) | 200 μL |
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| IGF2-EIF2AK2-20-AQAQ | 20 (40 μL) | 200 μL |
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IGF2 Gene Summary
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Name: Insulin Like Growth Factor 2
Chromosome: CHR11: 2150346 -2170833
Locus: 11p15.5
EIF2AK2 Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2
Chromosome: CHR2: 37333698 -37384190
Locus: 2p22.2
Gene Diseases
The IGF2 EIF2AK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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