IGF2-DDX27 Fusion FISH Probe
The IGF2-DDX27 Fusion FISH Probe is used to confirm a fusion of the IGF2 and DDX27 genes. The fusion of the IGF2 and DDX27 genes has been associated with Uterine Carcinosarcoma, and Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IGF2-DDX27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-RERE | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-REOR | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-REGO | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-REGR | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-REAQ | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-ORRE | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-OROR | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-ORGO | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-ORAQ | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-GORE | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-GOOR | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-GOGO | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-GOGR | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-GOAQ | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-GRRE | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-GROR | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-GRGO | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-GRGR | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-GRAQ | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-AQRE | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-AQOR | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-AQGO | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-AQGR | 20 (40 μL) | 200 μL |
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| IGF2-DDX27-20-AQAQ | 20 (40 μL) | 200 μL |
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IGF2 Gene Summary
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Name: Insulin Like Growth Factor 2
Chromosome: CHR11: 2150346 -2170833
Locus: 11p15.5
DDX27 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017]
Gene Name: DEAD-box Helicase 27
Chromosome: CHR20: 47835831 -47860614
Locus: 20q13.13
Gene Diseases
The IGF2 DDX27 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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