IGF2-CCT5 Fusion FISH Probe
The IGF2-CCT5 Fusion FISH Probe is used to confirm a fusion of the IGF2 and CCT5 genes. The fusion of the IGF2 and CCT5 genes has been associated with Colon Adenocarcinoma, and Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IGF2-CCT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-RERE | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-REOR | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-REGO | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-REGR | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-REAQ | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-ORRE | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-OROR | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-ORGO | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-ORAQ | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-GORE | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-GOOR | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-GOGO | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-GOGR | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-GOAQ | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-GRRE | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-GROR | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-GRGO | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-GRGR | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-GRAQ | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-AQRE | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-AQOR | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-AQGO | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-AQGR | 20 (40 μL) | 200 μL |
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| IGF2-CCT5-20-AQAQ | 20 (40 μL) | 200 μL |
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IGF2 Gene Summary
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Name: Insulin Like Growth Factor 2
Chromosome: CHR11: 2150346 -2170833
Locus: 11p15.5
CCT5 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
Gene Name: Chaperonin Containing TCP1 Subunit 5
Chromosome: CHR5: 10250281 -10266501
Locus: 5p15.2
Gene Diseases
The IGF2 CCT5 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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