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IGF1R-PRPS1 Fusion FISH Probe

The IGF1R-PRPS1 Fusion FISH Probe is used to confirm a fusion of the IGF1R and PRPS1 genes. The fusion of the IGF1R and PRPS1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
IGF1R-PRPS1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
IGF1R-PRPS1-20-RERE 20 (40 μL) 200 μL
IGF1R-PRPS1-20-REOR 20 (40 μL) 200 μL
IGF1R-PRPS1-20-REGO 20 (40 μL) 200 μL
IGF1R-PRPS1-20-REGR 20 (40 μL) 200 μL
IGF1R-PRPS1-20-REAQ 20 (40 μL) 200 μL
IGF1R-PRPS1-20-ORRE 20 (40 μL) 200 μL
IGF1R-PRPS1-20-OROR 20 (40 μL) 200 μL
IGF1R-PRPS1-20-ORGO 20 (40 μL) 200 μL
IGF1R-PRPS1-20-ORAQ 20 (40 μL) 200 μL
IGF1R-PRPS1-20-GORE 20 (40 μL) 200 μL
IGF1R-PRPS1-20-GOOR 20 (40 μL) 200 μL
IGF1R-PRPS1-20-GOGO 20 (40 μL) 200 μL
IGF1R-PRPS1-20-GOGR 20 (40 μL) 200 μL
IGF1R-PRPS1-20-GOAQ 20 (40 μL) 200 μL
IGF1R-PRPS1-20-GRRE 20 (40 μL) 200 μL
IGF1R-PRPS1-20-GROR 20 (40 μL) 200 μL
IGF1R-PRPS1-20-GRGO 20 (40 μL) 200 μL
IGF1R-PRPS1-20-GRGR 20 (40 μL) 200 μL
IGF1R-PRPS1-20-GRAQ 20 (40 μL) 200 μL
IGF1R-PRPS1-20-AQRE 20 (40 μL) 200 μL
IGF1R-PRPS1-20-AQOR 20 (40 μL) 200 μL
IGF1R-PRPS1-20-AQGO 20 (40 μL) 200 μL
IGF1R-PRPS1-20-AQGR 20 (40 μL) 200 μL
IGF1R-PRPS1-20-AQAQ 20 (40 μL) 200 μL

IGF1R Gene Summary

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Gene Name: Insulin Like Growth Factor 1 Receptor

Chromosome: CHR15: 99192760 -99507759

Locus: 15q26.3

PRPS1 Gene Summary

This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

Gene Name: Phosphoribosyl Pyrophosphate Synthetase 1

Chromosome: CHRX: 106871653 -106894256

Locus: Xq22.3

Gene Diseases

The IGF1R PRPS1 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.