IFT81-ACACB Fusion FISH Probe
The IFT81-ACACB Fusion FISH Probe is used to confirm a fusion of the IFT81 and ACACB genes. The fusion of the IFT81 and ACACB genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IFT81-ACACB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-RERE | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-REOR | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-REGO | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-REGR | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-REAQ | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-ORRE | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-OROR | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-ORGO | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-ORAQ | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-GORE | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-GOOR | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-GOGO | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-GOGR | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-GOAQ | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-GRRE | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-GROR | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-GRGO | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-GRGR | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-GRAQ | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-AQRE | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-AQOR | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-AQGO | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-AQGR | 20 (40 μL) | 200 μL |
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| IFT81-ACACB-20-AQAQ | 20 (40 μL) | 200 μL |
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ACACB Gene Summary
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Acetyl-CoA Carboxylase Beta
Chromosome: CHR12: 109577201 -109706030
Locus: 12q24.11
IFT81 Gene Summary
The protein encoded by this gene, together with IFT74, forms a tubulin-binding module of intraflagellar transport complex B. This module is involved in transport of tubulin within the cilium, and the encoded protein is required for ciliogenesis. Mutations in this gene are a cause of short-rib polydactyly syndromes. [provided by RefSeq, Dec 2016]
Gene Name: Intraflagellar Transport 81
Chromosome: CHR12: 110562139 -110656600
Locus: 12q24.11
Gene Diseases
The IFT81 ACACB Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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