IFT74-WNK2 Fusion FISH Probe
The IFT74-WNK2 Fusion FISH Probe is used to confirm a fusion of the IFT74 and WNK2 genes. The fusion of the IFT74 and WNK2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IFT74-WNK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-RERE | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-REOR | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-REGO | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-REGR | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-REAQ | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-ORRE | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-OROR | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-ORGO | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-GORE | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-GOOR | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-GOGO | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-GOGR | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-GRRE | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-GROR | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-GRGO | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-GRGR | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-AQRE | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-AQOR | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-AQGO | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-AQGR | 20 (40 μL) | 200 μL |
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| IFT74-WNK2-20-AQAQ | 20 (40 μL) | 200 μL |
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WNK2 Gene Summary
The protein encoded by this gene is a cytoplasmic serine-threonine kinase that belongs to the protein kinase superfamily. The protein plays an important role in the regulation of electrolyte homeostasis, cell signaling survival, and proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: WNK Lysine Deficient Protein Kinase 2
Chromosome: CHR9: 95947211 -96082854
Locus: 9q22.31
IFT74 Gene Summary
This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome. [provided by RefSeq, Mar 2017]
Gene Name: Intraflagellar Transport 74
Chromosome: CHR9: 26947036 -27062931
Locus: 9p21.2
Gene Diseases
The IFT74 WNK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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