IFT52-HCK Fusion FISH Probe
The IFT52-HCK Fusion FISH Probe is used to confirm a fusion of the IFT52 and HCK genes. The fusion of the IFT52 and HCK genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IFT52-HCK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-RERE | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-REOR | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-REGO | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-REGR | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-OROR | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-GORE | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-GROR | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| IFT52-HCK-20-AQAQ | 20 (40 μL) | 200 μL |
|
HCK Gene Summary
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010]
Gene Name: HCK Proto-oncogene, Src Family Tyrosine Kinase
Chromosome: CHR20: 30639990 -30689657
Locus: 20q11.21
IFT52 Gene Summary
This gene encodes a conserved proline-rich protein that is a component of the intraflagellar transport-B (IFT-B) core complex. The encoded protein is essential for the integrity of the IFT-B core complex, and for biosynthesis and maintenance of cilia. Mutations in this gene are associated with ciliopathy that affects the skeleton. [provided by RefSeq, Oct 2016]
Gene Name: Intraflagellar Transport 52
Chromosome: CHR20: 42219578 -42275862
Locus: 20q13.12
Gene Diseases
The IFT52 HCK Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|