IFT140-ABCA3 Fusion FISH Probe
The IFT140-ABCA3 Fusion FISH Probe is used to confirm a fusion of the IFT140 and ABCA3 genes. The fusion of the IFT140 and ABCA3 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IFT140-ABCA3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| IFT140-ABCA3-20-AQAQ | 20 (40 μL) | 200 μL |
|
ABCA3 Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The full transporter encoded by this gene may be involved in development of resistance to xenobiotics and engulfment during programmed cell death. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily A Member 3
Chromosome: CHR16: 2325878 -2390747
Locus: 16p13.3
IFT140 Gene Summary
This gene encodes one of the subunits of the intraflagellar transport (IFT) complex A. Intraflagellar transport is involved in the genesis, resorption and signaling of primary cilia. The primary cilium is a microtubule-based sensory organelle at the surface of most quiescent mammalian cells, that receives signals from its environment, such as the flow of fluid, light or odors, and transduces those signals to the nucleus. Loss of the corresponding protein in mouse results in renal cystic disease. [provided by RefSeq, Jun 2012]
Gene Name: Intraflagellar Transport 140
Chromosome: CHR16: 1560427 -1662109
Locus: 16p13.3
Gene Diseases
The IFT140 ABCA3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|