IDH3A-DHX32 Fusion FISH Probe
The IDH3A-DHX32 Fusion FISH Probe is used to confirm a fusion of the IDH3A and DHX32 genes. The fusion of the IDH3A and DHX32 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IDH3A-DHX32-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-RERE | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-REOR | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-REGO | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-REGR | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-REAQ | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-ORRE | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-OROR | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-ORGO | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-ORAQ | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-GORE | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-GOOR | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-GOGO | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-GOGR | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-GOAQ | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-GRRE | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-GROR | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-GRGO | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-GRGR | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-GRAQ | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-AQRE | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-AQOR | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-AQGO | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-AQGR | 20 (40 μL) | 200 μL |
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| IDH3A-DHX32-20-AQAQ | 20 (40 μL) | 200 μL |
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IDH3A Gene Summary
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008]
Gene Name: Isocitrate Dehydrogenase 3 (NAD(+)) Alpha
Chromosome: CHR15: 78441718 -78462884
Locus: 15q25.1
DHX32 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants, but the full length nature of one of the variants has not been defined. [provided by RefSeq, Jul 2008]
Gene Name: DEAH-box Helicase 32 (putative)
Chromosome: CHR10: 127524908 -127569884
Locus: 10q26.2
Gene Diseases
The IDH3A DHX32 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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