HSPB1-MYO1B Fusion FISH Probe
The HSPB1-MYO1B Fusion FISH Probe is used to confirm a fusion of the HSPB1 and MYO1B genes. The fusion of the HSPB1 and MYO1B genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HSPB1-MYO1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-RERE | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-REOR | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-REGO | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-REGR | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-REAQ | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-ORRE | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-OROR | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-ORGO | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-GORE | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-GOOR | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-GOGO | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-GOGR | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-GRRE | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-GROR | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-GRGO | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-GRGR | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-AQRE | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-AQOR | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-AQGO | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-AQGR | 20 (40 μL) | 200 μL |
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| HSPB1-MYO1B-20-AQAQ | 20 (40 μL) | 200 μL |
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HSPB1 Gene Summary
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]
Gene Name: Heat Shock Protein Family B (small) Member 1
Chromosome: CHR7: 75931874 -75933614
Locus: 7q11.23
MYO1B Gene Summary
The Myosin IB (MYO1B) gene is located on chr2 :192110106-192290115 at 2q32.3.
Gene Name: Myosin IB
Chromosome: CHR2: 192110106 -192290115
Locus: 2q32.3
Gene Diseases
The HSPB1 MYO1B Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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