HSD17B4-TNFAIP8 Fusion FISH Probe
The HSD17B4-TNFAIP8 Fusion FISH Probe is used to confirm a fusion of the HSD17B4 and TNFAIP8 genes. The fusion of the HSD17B4 and TNFAIP8 genes has been associated with Stomach Adenocarcinoma, and Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HSD17B4-TNFAIP8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-RERE | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-REOR | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-REGO | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-REGR | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-REAQ | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-ORRE | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-OROR | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-ORGO | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-ORAQ | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-GORE | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-GOOR | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-GOGO | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-GOGR | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-GOAQ | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-GRRE | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-GROR | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-GRGO | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-GRGR | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-GRAQ | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-AQRE | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-AQOR | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-AQGO | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-AQGR | 20 (40 μL) | 200 μL |
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| HSD17B4-TNFAIP8-20-AQAQ | 20 (40 μL) | 200 μL |
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HSD17B4 Gene Summary
The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Gene Name: Hydroxysteroid 17-beta Dehydrogenase 4
Chromosome: CHR5: 118788137 -118878030
Locus: 5q23.1
TNFAIP8 Gene Summary
The TNF Alpha Induced Protein 8 (TNFAIP8) gene is located on chr5 :118604417-118730294 at 5q23.1.
Gene Name: TNF Alpha Induced Protein 8
Chromosome: CHR5: 118604417 -118730294
Locus: 5q23.1
Gene Diseases
The HSD17B4 TNFAIP8 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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