HSD17B3-ENPP2 Fusion FISH Probe
The HSD17B3-ENPP2 Fusion FISH Probe is used to confirm a fusion of the HSD17B3 and ENPP2 genes. The fusion of the HSD17B3 and ENPP2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HSD17B3-ENPP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-RERE | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-REOR | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-REGO | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-REGR | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-REAQ | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-ORRE | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-OROR | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-ORGO | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-GORE | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-GOOR | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-GOGO | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-GOGR | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-GRRE | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-GROR | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-GRGO | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-GRGR | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-AQRE | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-AQOR | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-AQGO | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-AQGR | 20 (40 μL) | 200 μL |
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| HSD17B3-ENPP2-20-AQAQ | 20 (40 μL) | 200 μL |
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HSD17B3 Gene Summary
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008]
Gene Name: Hydroxysteroid 17-beta Dehydrogenase 3
Chromosome: CHR9: 98997588 -99064434
Locus: 9q22.32
ENPP2 Gene Summary
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]
Gene Name: Ectonucleotide Pyrophosphatase/phosphodiesterase 2
Chromosome: CHR8: 120569318 -120651106
Locus: 8q24.12
Gene Diseases
The HSD17B3 ENPP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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