HS6ST3-ACTR1A Fusion FISH Probe
The HS6ST3-ACTR1A Fusion FISH Probe is used to confirm a fusion of the HS6ST3 and ACTR1A genes. The fusion of the HS6ST3 and ACTR1A genes has been associated with Pheochromocytoma And Paraganglioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HS6ST3-ACTR1A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-RERE | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-REOR | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-REGO | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-REGR | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-REAQ | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-ORRE | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-OROR | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-ORGO | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-ORAQ | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-GORE | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-GOOR | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-GOGO | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-GOGR | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-GOAQ | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-GRRE | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-GROR | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-GRGO | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-GRGR | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-GRAQ | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-AQRE | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-AQOR | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-AQGO | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-AQGR | 20 (40 μL) | 200 μL |
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| HS6ST3-ACTR1A-20-AQAQ | 20 (40 μL) | 200 μL |
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ACTR1A Gene Summary
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq, Jul 2008]
Gene Name: ARP1 Actin Related Protein 1 Homolog A
Chromosome: CHR10: 104238985 -104262512
Locus: 10q24.32
HS6ST3 Gene Summary
Heparan sulfate (HS) sulfotransferases, such as HS6ST3, modify HS to generate structures required for interactions between HS and a variety of proteins. These interactions are implicated in proliferation and differentiation, adhesion, migration, inflammation, blood coagulation, and other diverse processes (Habuchi et al., 2000 [PubMed 10644753]).[supplied by OMIM, Mar 2008]
Gene Name: Heparan Sulfate 6-O-sulfotransferase 3
Chromosome: CHR13: 96743092 -97491812
Locus: 13q32.1
Gene Diseases
The HS6ST3 ACTR1A Fusion has been associated with the following diseases:
| Disease Name |
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| Pheochromocytoma And Paraganglioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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