HS2ST1-PRDX1 Fusion FISH Probe
The HS2ST1-PRDX1 Fusion FISH Probe is used to confirm a fusion of the HS2ST1 and PRDX1 genes. The fusion of the HS2ST1 and PRDX1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HS2ST1-PRDX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-RERE | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-REOR | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-REGO | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-REGR | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-REAQ | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-ORRE | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-OROR | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-ORGO | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-GORE | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-GOOR | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-GOGO | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-GOGR | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-GRRE | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-GROR | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-GRGO | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-GRGR | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-AQRE | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-AQOR | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-AQGO | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-AQGR | 20 (40 μL) | 200 μL |
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| HS2ST1-PRDX1-20-AQAQ | 20 (40 μL) | 200 μL |
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PRDX1 Gene Summary
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]
Gene Name: Peroxiredoxin 1
Chromosome: CHR1: 45976706 -45988562
Locus: 1p34.1
HS2ST1 Gene Summary
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Name: Heparan Sulfate 2-O-sulfotransferase 1
Chromosome: CHR1: 87380334 -87575681
Locus: 1p22.3
Gene Diseases
The HS2ST1 PRDX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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