HPSE2-CWF19L1 Fusion FISH Probe
The HPSE2-CWF19L1 Fusion FISH Probe is used to confirm a fusion of the HPSE2 and CWF19L1 genes. The fusion of the HPSE2 and CWF19L1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HPSE2-CWF19L1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-RERE | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-REOR | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-REGO | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-REGR | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-REAQ | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-ORRE | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-OROR | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-ORGO | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-ORAQ | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-GORE | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-GOOR | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-GOGO | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-GOGR | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-GOAQ | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-GRRE | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-GROR | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-GRGO | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-GRGR | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-GRAQ | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-AQRE | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-AQOR | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-AQGO | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-AQGR | 20 (40 μL) | 200 μL |
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| HPSE2-CWF19L1-20-AQAQ | 20 (40 μL) | 200 μL |
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CWF19L1 Gene Summary
This gene encodes a member of the CWF19 protein family. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia-17 and mild cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: CWF19 Like 1, Cell Cycle Control (S. Pombe)
Chromosome: CHR10: 101992054 -102027437
Locus: 10q24.31
HPSE2 Gene Summary
This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: Heparanase 2 (inactive)
Chromosome: CHR10: 100216833 -100995632
Locus: 10q24.2
Gene Diseases
The HPSE2 CWF19L1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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