HPRT1-LRRC2 Fusion FISH Probe
The HPRT1-LRRC2 Fusion FISH Probe is used to confirm a fusion of the HPRT1 and LRRC2 genes. The fusion of the HPRT1 and LRRC2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HPRT1-LRRC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-RERE | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-REOR | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-REGO | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-REGR | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-REAQ | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-ORRE | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-OROR | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-ORGO | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-GORE | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-GOOR | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-GOGO | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-GOGR | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-GRRE | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-GROR | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-GRGO | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-GRGR | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-AQRE | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-AQOR | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-AQGO | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-AQGR | 20 (40 μL) | 200 μL |
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| HPRT1-LRRC2-20-AQAQ | 20 (40 μL) | 200 μL |
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HPRT1 Gene Summary
The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009]
Gene Name: Hypoxanthine Phosphoribosyltransferase 1
Chromosome: CHRX: 133594174 -133634698
Locus: Xq26.2-q26.3
LRRC2 Gene Summary
This gene encodes a member of the leucine-rich repeat-containing family of proteins, which function in diverse biological pathways. This family member may possibly be a nuclear protein. Similarity to the RAS suppressor protein, as well as expression down-regulation observed in tumor cells, suggests that it may function as a tumor suppressor. The gene is located in the chromosome 3 common eliminated region 1 (C3CER1), a 1.4 Mb region that is commonly deleted in diverse tumors. A related pseudogene has been identified on chromosome 2. [provided by RefSeq, Sep 2011]
Gene Name: Leucine Rich Repeat Containing 2
Chromosome: CHR3: 46556877 -46608040
Locus: 3p21.31
Gene Diseases
The HPRT1 LRRC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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