HPN-PPP2R5C Fusion FISH Probe
The HPN-PPP2R5C Fusion FISH Probe is used to confirm a fusion of the HPN and PPP2R5C genes. The fusion of the HPN and PPP2R5C genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HPN-PPP2R5C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-RERE | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-REOR | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-REGO | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-REGR | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-REAQ | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-ORRE | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-OROR | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-ORGO | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-ORAQ | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-GORE | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-GOOR | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-GOGO | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-GOGR | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-GOAQ | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-GRRE | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-GROR | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-GRGO | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-GRGR | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-GRAQ | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-AQRE | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-AQOR | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-AQGO | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-AQGR | 20 (40 μL) | 200 μL |
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| HPN-PPP2R5C-20-AQAQ | 20 (40 μL) | 200 μL |
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HPN Gene Summary
This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Name: Hepsin
Chromosome: CHR19: 35531409 -35557477
Locus: 19q13.11
PPP2R5C Gene Summary
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Protein Phosphatase 2 Regulatory Subunit B'gamma
Chromosome: CHR14: 102228134 -102394328
Locus: 14q32.31
Gene Diseases
The HPN PPP2R5C Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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