HOXB6-PITPNC1 Fusion FISH Probe
The HOXB6-PITPNC1 Fusion FISH Probe is used to confirm a fusion of the HOXB6 and PITPNC1 genes. The fusion of the HOXB6 and PITPNC1 genes has been associated with Lymphoid Neoplasm Diffuse Large B-cell Lymphoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HOXB6-PITPNC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-RERE | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-REOR | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-REGO | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-REGR | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-REAQ | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-ORRE | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-OROR | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-ORGO | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-GORE | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-GOOR | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-GOGO | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-GOGR | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-GRRE | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-GROR | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-GRGO | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-GRGR | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-AQRE | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-AQOR | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-AQGO | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-AQGR | 20 (40 μL) | 200 μL |
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| HOXB6-PITPNC1-20-AQAQ | 20 (40 μL) | 200 μL |
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HOXB6 Gene Summary
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer. [provided by RefSeq, Jul 2008]
Gene Name: Homeobox B6
Chromosome: CHR17: 46673098 -46682334
Locus: 17q21.32
PITPNC1 Gene Summary
This gene encodes a member of the phosphatidylinositol transfer protein family. The encoded cytoplasmic protein plays a role in multiple processes including cell signaling and lipid metabolism by facilitating the transfer of phosphatidylinositol between membrane compartments. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 1. [provided by RefSeq, May 2012]
Gene Name: Phosphatidylinositol Transfer Protein, Cytoplasmic 1
Chromosome: CHR17: 65373923 -65689647
Locus: 17q24.2
Gene Diseases
The HOXB6 PITPNC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lymphoid Neoplasm Diffuse Large B-cell Lymphoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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