HOXB3-FAP Fusion FISH Probe
The HOXB3-FAP Fusion FISH Probe is used to confirm a fusion of the HOXB3 and FAP genes. The fusion of the HOXB3 and FAP genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HOXB3-FAP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-RERE | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-REOR | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-REGO | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-REGR | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-REAQ | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-ORRE | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-OROR | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-ORGO | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-ORAQ | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-GORE | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-GOOR | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-GOGO | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-GOGR | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-GOAQ | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-GRRE | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-GROR | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-GRGO | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-GRGR | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-GRAQ | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-AQRE | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-AQOR | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-AQGO | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-AQGR | 20 (40 μL) | 200 μL |
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| HOXB3-FAP-20-AQAQ | 20 (40 μL) | 200 μL |
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FAP Gene Summary
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Name: Fibroblast Activation Protein Alpha
Chromosome: CHR2: 163027199 -163100045
Locus: 2q24.2
HOXB3 Gene Summary
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). [provided by RefSeq, Jul 2008]
Gene Name: Homeobox B3
Chromosome: CHR17: 46626231 -46651810
Locus: 17q21.32
Gene Diseases
The HOXB3 FAP Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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