HOOK3-MTFR1 Fusion FISH Probe
The HOOK3-MTFR1 Fusion FISH Probe is used to confirm a fusion of the HOOK3 and MTFR1 genes. The fusion of the HOOK3 and MTFR1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HOOK3-MTFR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-RERE | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-REOR | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-REGO | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-REGR | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-REAQ | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-ORRE | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-OROR | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-ORGO | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-ORAQ | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-GORE | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-GOOR | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-GOGO | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-GOGR | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-GOAQ | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-GRRE | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-GROR | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-GRGO | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-GRGR | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-GRAQ | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-AQRE | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-AQOR | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-AQGO | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-AQGR | 20 (40 μL) | 200 μL |
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| HOOK3-MTFR1-20-AQAQ | 20 (40 μL) | 200 μL |
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MTFR1 Gene Summary
This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X. [provided by RefSeq, Mar 2009]
Gene Name: Mitochondrial Fission Regulator 1
Chromosome: CHR8: 66556887 -66622798
Locus: 8q13.1
HOOK3 Gene Summary
Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]
Gene Name: Hook Microtubule Tethering Protein 3
Chromosome: CHR8: 42752032 -42885682
Locus: 8p11.21
Gene Diseases
The HOOK3 MTFR1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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