HOOK3-BAALC Fusion FISH Probe
The HOOK3-BAALC Fusion FISH Probe is used to confirm a fusion of the HOOK3 and BAALC genes. The fusion of the HOOK3 and BAALC genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HOOK3-BAALC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-RERE | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-REOR | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-REGO | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-REGR | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-REAQ | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-ORRE | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-OROR | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-ORGO | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-ORAQ | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-GORE | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-GOOR | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-GOGO | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-GOGR | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-GOAQ | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-GRRE | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-GROR | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-GRGO | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-GRGR | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-GRAQ | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-AQRE | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-AQOR | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-AQGO | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-AQGR | 20 (40 μL) | 200 μL |
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| HOOK3-BAALC-20-AQAQ | 20 (40 μL) | 200 μL |
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BAALC Gene Summary
This gene was identified by gene expression studies in patients with acute myeloid leukemia (AML). The gene is conserved among mammals and is not found in lower organisms. Tissues that express this gene develop from the neuroectoderm. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene; however, some of the transcript variants are found only in AML cell lines. [provided by RefSeq, Jul 2008]
Gene Name: BAALC, MAP3K1 And KLF4 Binding
Chromosome: CHR8: 104152920 -104242533
Locus: 8q22.3
HOOK3 Gene Summary
Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]
Gene Name: Hook Microtubule Tethering Protein 3
Chromosome: CHR8: 42752032 -42885682
Locus: 8p11.21
Gene Diseases
The HOOK3 BAALC Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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