HOOK2-NFIX Fusion FISH Probe
The HOOK2-NFIX Fusion FISH Probe is used to confirm a fusion of the HOOK2 and NFIX genes. The fusion of the HOOK2 and NFIX genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HOOK2-NFIX-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-RERE | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-REOR | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-REGO | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-REGR | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-REAQ | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-ORRE | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-OROR | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-ORGO | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-ORAQ | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-GORE | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-GOOR | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-GOGO | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-GOGR | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-GOAQ | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-GRRE | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-GROR | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-GRGO | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-GRGR | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-GRAQ | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-AQRE | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-AQOR | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-AQGO | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-AQGR | 20 (40 μL) | 200 μL |
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| HOOK2-NFIX-20-AQAQ | 20 (40 μL) | 200 μL |
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NFIX Gene Summary
The protein encoded by this gene is a transcription factor that binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 in viral and cellular promoters. The encoded protein can also stimulate adenovirus replication in vitro. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
Gene Name: Nuclear Factor I X
Chromosome: CHR19: 13106583 -13209610
Locus: 19p13.13
HOOK2 Gene Summary
Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]
Gene Name: Hook Microtubule Tethering Protein 2
Chromosome: CHR19: 12873816 -12886434
Locus: 19p13.13
Gene Diseases
The HOOK2 NFIX Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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