HOOK2-MAST1 Fusion FISH Probe
The HOOK2-MAST1 Fusion FISH Probe is used to confirm a fusion of the HOOK2 and MAST1 genes. The fusion of the HOOK2 and MAST1 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HOOK2-MAST1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-RERE | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-REOR | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-REGO | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-REGR | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-REAQ | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-ORRE | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-OROR | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-ORGO | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-ORAQ | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-GORE | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-GOOR | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-GOGO | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-GOGR | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-GOAQ | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-GRRE | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-GROR | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-GRGO | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-GRGR | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-GRAQ | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-AQRE | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-AQOR | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-AQGO | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-AQGR | 20 (40 μL) | 200 μL |
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| HOOK2-MAST1-20-AQAQ | 20 (40 μL) | 200 μL |
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MAST1 Gene Summary
This gene is a member of the microtubule-associated serine/threonine kinase (MAST) family. The protein encoded by this gene has an N-terminal serine/threonine kinase domain followed by a postsynaptic density protein-95/discs large/zona occludens-1 (PDZ) domain. In mouse and rat, the orthologous protein associates with the cytoskeleton and can bind both beta-2-syntrophin and neuronal nitric oxide synthase (nNOS) through its PDZ domain. In mouse and rat, this protein also co-localizes with dystrophin- and utrophin-associated protein complexes (DAPC/UAPC) in the vascular endothelium of the central nervous system. [provided by RefSeq, May 2017]
Gene Name: Microtubule Associated Serine/threonine Kinase 1
Chromosome: CHR19: 12949258 -12985766
Locus: 19p13.13
HOOK2 Gene Summary
Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]
Gene Name: Hook Microtubule Tethering Protein 2
Chromosome: CHR19: 12873816 -12886434
Locus: 19p13.13
Gene Diseases
The HOOK2 MAST1 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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