HNRNPH3-SLC29A3 Fusion FISH Probe
The HNRNPH3-SLC29A3 Fusion FISH Probe is used to confirm a fusion of the HNRNPH3 and SLC29A3 genes. The fusion of the HNRNPH3 and SLC29A3 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HNRNPH3-SLC29A3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-RERE | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-REOR | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-REGO | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-REGR | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-REAQ | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-ORRE | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-OROR | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-ORGO | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-ORAQ | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-GORE | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-GOOR | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-GOGO | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-GOGR | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-GOAQ | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-GRRE | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-GROR | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-GRGO | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-GRGR | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-GRAQ | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-AQRE | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-AQOR | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-AQGO | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-AQGR | 20 (40 μL) | 200 μL |
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| HNRNPH3-SLC29A3-20-AQAQ | 20 (40 μL) | 200 μL |
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HNRNPH3 Gene Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized. [provided by RefSeq, Jul 2008]
Gene Name: Heterogeneous Nuclear Ribonucleoprotein H3
Chromosome: CHR10: 70091767 -70102953
Locus: 10q21.3
SLC29A3 Gene Summary
This gene encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2010]
Gene Name: Solute Carrier Family 29 Member 3
Chromosome: CHR10: 73079009 -73123147
Locus: 10q22.1
Gene Diseases
The HNRNPH3 SLC29A3 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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