HNRNPH1-INSR Fusion FISH Probe
The HNRNPH1-INSR Fusion FISH Probe is used to confirm a fusion of the HNRNPH1 and INSR genes. The fusion of the HNRNPH1 and INSR genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HNRNPH1-INSR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-RERE | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-REOR | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-REGO | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-REGR | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-OROR | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-GORE | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-GROR | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| HNRNPH1-INSR-20-AQAQ | 20 (40 μL) | 200 μL |
|
HNRNPH1 Gene Summary
This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012]
Gene Name: Heterogeneous Nuclear Ribonucleoprotein H1
Chromosome: CHR5: 179041178 -179050722
Locus: 5q35.3
INSR Gene Summary
This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Gene Name: Insulin Receptor
Chromosome: CHR19: 7112265 -7294011
Locus: 19p13.2
Gene Diseases
The HNRNPH1 INSR Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|