HNRNPC-PAPOLA Fusion FISH Probe
The HNRNPC-PAPOLA Fusion FISH Probe is used to confirm a fusion of the HNRNPC and PAPOLA genes. The fusion of the HNRNPC and PAPOLA genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HNRNPC-PAPOLA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-RERE | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-REOR | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-REGR | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-OROR | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| HNRNPC-PAPOLA-20-AQAQ | 20 (40 μL) | 200 μL |
|
HNRNPC Gene Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Heterogeneous Nuclear Ribonucleoprotein C (C1/C2)
Chromosome: CHR14: 21677295 -21737638
Locus: 14q11.2
PAPOLA Gene Summary
The protein encoded by this gene belongs to the poly(A) polymerase family. It is required for the addition of adenosine residues for the creation of the 3'-poly(A) tail of mRNAs. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Poly(A) Polymerase Alpha
Chromosome: CHR14: 96968719 -97033448
Locus: 14q32.2
Gene Diseases
The HNRNPC PAPOLA Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|