HNRNPC-CHD8 Fusion FISH Probe
The HNRNPC-CHD8 Fusion FISH Probe is used to confirm a fusion of the HNRNPC and CHD8 genes. The fusion of the HNRNPC and CHD8 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HNRNPC-CHD8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-RERE | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-REOR | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-REGO | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-REGR | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-REAQ | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-ORRE | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-OROR | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-ORGO | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-ORAQ | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-GORE | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-GOOR | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-GOGO | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-GOGR | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-GOAQ | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-GRRE | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-GROR | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-GRGO | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-GRGR | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-GRAQ | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-AQRE | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-AQOR | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-AQGO | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-AQGR | 20 (40 μL) | 200 μL |
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| HNRNPC-CHD8-20-AQAQ | 20 (40 μL) | 200 μL |
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HNRNPC Gene Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Heterogeneous Nuclear Ribonucleoprotein C (C1/C2)
Chromosome: CHR14: 21677295 -21737638
Locus: 14q11.2
CHD8 Gene Summary
This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which are common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. This gene has been shown to function in several processes that include transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Allelic variants of this gene are associated with autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]
Gene Name: Chromodomain Helicase DNA Binding Protein 8
Chromosome: CHR14: 21853352 -21905457
Locus: 14q11.2
Gene Diseases
The HNRNPC CHD8 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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