HNRNPA2B1-SIAE Fusion FISH Probe
The HNRNPA2B1-SIAE Fusion FISH Probe is used to confirm a fusion of the HNRNPA2B1 and SIAE genes. The fusion of the HNRNPA2B1 and SIAE genes has been associated with Lung Adenocarcinoma, and Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HNRNPA2B1-SIAE-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-RERE | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-REOR | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-REGO | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-REGR | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-REAQ | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-ORRE | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-OROR | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-ORGO | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-ORAQ | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-GORE | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-GOOR | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-GOGO | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-GOGR | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-GOAQ | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-GRRE | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-GROR | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-GRGO | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-GRGR | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-GRAQ | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-AQRE | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-AQOR | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-AQGO | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-AQGR | 20 (40 μL) | 200 μL |
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| HNRNPA2B1-SIAE-20-AQAQ | 20 (40 μL) | 200 μL |
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HNRNPA2B1 Gene Summary
This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Heterogeneous Nuclear Ribonucleoprotein A2/B1
Chromosome: CHR7: 26229555 -26240413
Locus: 7p15.2
SIAE Gene Summary
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Name: Sialic Acid Acetylesterase
Chromosome: CHR11: 124505684 -124546199
Locus: 11q24.2
Gene Diseases
The HNRNPA2B1 SIAE Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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