HMGXB3-CAPN1 Fusion FISH Probe
The HMGXB3-CAPN1 Fusion FISH Probe is used to confirm a fusion of the HMGXB3 and CAPN1 genes. The fusion of the HMGXB3 and CAPN1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HMGXB3-CAPN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-RERE | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-REOR | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-REGO | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-REGR | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-REAQ | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-ORRE | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-OROR | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-ORGO | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-GORE | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-GOOR | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-GOGO | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-GOGR | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-GRRE | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-GROR | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-GRGO | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-GRGR | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-AQRE | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-AQOR | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-AQGO | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-AQGR | 20 (40 μL) | 200 μL |
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| HMGXB3-CAPN1-20-AQAQ | 20 (40 μL) | 200 μL |
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CAPN1 Gene Summary
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Gene Name: Calpain 1
Chromosome: CHR11: 64948685 -64979477
Locus: 11q13.1
HMGXB3 Gene Summary
This gene is one of the non-canonical high mobility group (HMG) genes. The encoded protein contains an HMG-box domain found in DNA binding proteins such as transcription factors and chromosomal proteins. [provided by RefSeq, Aug 2011]
Gene Name: HMG-box Containing 3
Chromosome: CHR5: 149380168 -149432706
Locus: 5q32
Gene Diseases
The HMGXB3 CAPN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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