HMGA2-KALRN Fusion FISH Probe
The HMGA2-KALRN Fusion FISH Probe is used to confirm a fusion of the HMGA2 and KALRN genes. The fusion of the HMGA2 and KALRN genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HMGA2-KALRN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-RERE | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-REOR | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-REGO | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-REGR | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-OROR | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-GORE | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-GROR | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| HMGA2-KALRN-20-AQAQ | 20 (40 μL) | 200 μL |
|
HMGA2 Gene Summary
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: High Mobility Group AT-hook 2
Chromosome: CHR12: 66218239 -66360071
Locus: 12q14.3
KALRN Gene Summary
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016]
Gene Name: Kalirin RhoGEF Kinase
Chromosome: CHR3: 123813557 -124440036
Locus: 3q21.1-q21.2
Gene Diseases
The HMGA2 KALRN Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|