HMGA2-DAB1 Fusion FISH Probe
The HMGA2-DAB1 Fusion FISH Probe is used to confirm a fusion of the HMGA2 and DAB1 genes. The fusion of the HMGA2 and DAB1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HMGA2-DAB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-RERE | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-REOR | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-REGO | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-REGR | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-REAQ | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-ORRE | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-OROR | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-ORGO | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-GORE | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-GOOR | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-GOGO | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-GOGR | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-GRRE | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-GROR | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-GRGO | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-GRGR | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-AQRE | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-AQOR | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-AQGO | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-AQGR | 20 (40 μL) | 200 μL |
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| HMGA2-DAB1-20-AQAQ | 20 (40 μL) | 200 μL |
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DAB1 Gene Summary
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]
Gene Name: DAB1, Reelin Adaptor Protein
Chromosome: CHR1: 57463578 -58716211
Locus: 1p32.2
HMGA2 Gene Summary
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: High Mobility Group AT-hook 2
Chromosome: CHR12: 66218239 -66360071
Locus: 12q14.3
Gene Diseases
The HMGA2 DAB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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