HMCN1-RNF2 Fusion FISH Probe
The HMCN1-RNF2 Fusion FISH Probe is used to confirm a fusion of the HMCN1 and RNF2 genes. The fusion of the HMCN1 and RNF2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HMCN1-RNF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-RERE | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-REOR | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-REGO | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-REGR | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-REAQ | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-ORRE | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-OROR | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-ORGO | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-GORE | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-GOOR | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-GOGO | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-GOGR | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-GRRE | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-GROR | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-GRGO | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-GRGR | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-AQRE | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-AQOR | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-AQGO | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-AQGR | 20 (40 μL) | 200 μL |
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| HMCN1-RNF2-20-AQAQ | 20 (40 μL) | 200 μL |
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RNF2 Gene Summary
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. [provided by RefSeq, Jul 2008]
Gene Name: Ring Finger Protein 2
Chromosome: CHR1: 185014550 -185071740
Locus: 1q25.3
HMCN1 Gene Summary
This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008]
Gene Name: Hemicentin 1
Chromosome: CHR1: 185703682 -186160085
Locus: 1q25.3-q31.1
Gene Diseases
The HMCN1 RNF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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