HLCS-STRA8 Fusion FISH Probe
The HLCS-STRA8 Fusion FISH Probe is used to confirm a fusion of the HLCS and STRA8 genes. The fusion of the HLCS and STRA8 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HLCS-STRA8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-RERE | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-REOR | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-REGO | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-REGR | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-REAQ | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-ORRE | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-OROR | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-ORGO | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-ORAQ | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-GORE | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-GOOR | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-GOGO | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-GOGR | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-GOAQ | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-GRRE | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-GROR | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-GRGO | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-GRGR | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-GRAQ | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-AQRE | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-AQOR | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-AQGO | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-AQGR | 20 (40 μL) | 200 μL |
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| HLCS-STRA8-20-AQAQ | 20 (40 μL) | 200 μL |
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HLCS Gene Summary
This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jun 2011]
Gene Name: Holocarboxylase Synthetase
Chromosome: CHR21: 38123188 -38362545
Locus: 21q22.13
STRA8 Gene Summary
This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. [provided by RefSeq, Nov 2010]
Gene Name: Stimulated By Retinoic Acid 8
Chromosome: CHR7: 134916730 -134943244
Locus: 7q33
Gene Diseases
The HLCS STRA8 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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