HIVEP1-PTCRA Fusion FISH Probe
The HIVEP1-PTCRA Fusion FISH Probe is used to confirm a fusion of the HIVEP1 and PTCRA genes. The fusion of the HIVEP1 and PTCRA genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HIVEP1-PTCRA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-RERE | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-REOR | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-REGO | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-REGR | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-REAQ | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-ORRE | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-OROR | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-ORGO | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-ORAQ | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-GORE | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-GOOR | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-GOGO | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-GOGR | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-GOAQ | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-GRRE | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-GROR | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-GRGO | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-GRGR | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-GRAQ | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-AQRE | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-AQOR | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-AQGO | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-AQGR | 20 (40 μL) | 200 μL |
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| HIVEP1-PTCRA-20-AQAQ | 20 (40 μL) | 200 μL |
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HIVEP1 Gene Summary
This gene encodes a transcription factor belonging to the ZAS family, members of which are large proteins that contain a ZAS domain - a modular protein structure consisting of a pair of C2H2 zinc fingers with an acidic-rich region and a serine/threonine-rich sequence. These proteins bind specifically to the DNA sequence motif, GGGACTTTCC, found in the enhancer elements of several viral promoters, including human immunodeficiency virus (HIV), and to related sequences found in the enhancer elements of a number of cellular promoters. This protein binds to this sequence motif, suggesting a role in the transcriptional regulation of both viral and cellular genes. [provided by RefSeq, Oct 2011]
Gene Name: Human Immunodeficiency Virus Type I Enhancer Binding Protein 1
Chromosome: CHR6: 12012723 -12165232
Locus: 6p24.1
PTCRA Gene Summary
The protein encoded by this gene is a single-pass type I membrane protein that is found in immmature but not mature T-cells. Along with TCRB and CD3 complex, the encoded protein forms the pre-T-cell receptor complex, which regulates early T-cell development. Four transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
Gene Name: Pre T-cell Antigen Receptor Alpha
Chromosome: CHR6: 42883726 -42893575
Locus: 6p21.1
Gene Diseases
The HIVEP1 PTCRA Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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