HIST1H2BD-MDN1 Fusion FISH Probe
The HIST1H2BD-MDN1 Fusion FISH Probe is used to confirm a fusion of the HIST1H2BD and MDN1 genes. The fusion of the HIST1H2BD and MDN1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HIST1H2BD-MDN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-RERE | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-REOR | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-REGO | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-REGR | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-REAQ | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-ORRE | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-OROR | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-ORGO | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-GORE | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-GOOR | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-GOGO | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-GOGR | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-GRRE | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-GROR | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-GRGO | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-GRGR | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-AQRE | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-AQOR | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-AQGO | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-AQGR | 20 (40 μL) | 200 μL |
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| HIST1H2BD-MDN1-20-AQAQ | 20 (40 μL) | 200 μL |
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HIST1H2BD Gene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Two transcripts that encode the same protein have been identified for this gene, which is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
Gene Name: Histone Cluster 1 H2B Family Member D
Chromosome: CHR6: 26158348 -26171576
Locus: 6p22.2
MDN1 Gene Summary
The Midasin AAA ATPase 1 (MDN1) gene is located on chr6 :90353230-90529442 at 6q15.
Gene Name: Midasin AAA ATPase 1
Chromosome: CHR6: 90353230 -90529442
Locus: 6q15
Gene Diseases
The HIST1H2BD MDN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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