HIPK2-MYCBP2 Fusion FISH Probe
The HIPK2-MYCBP2 Fusion FISH Probe is used to confirm a fusion of the HIPK2 and MYCBP2 genes. The fusion of the HIPK2 and MYCBP2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HIPK2-MYCBP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-RERE | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-REOR | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-REGO | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-REGR | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-REAQ | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-ORRE | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-OROR | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-ORGO | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-GORE | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-GOOR | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-GOGO | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-GOGR | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-GRRE | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-GROR | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-GRGO | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-GRGR | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-AQRE | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-AQOR | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-AQGO | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-AQGR | 20 (40 μL) | 200 μL |
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| HIPK2-MYCBP2-20-AQAQ | 20 (40 μL) | 200 μL |
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MYCBP2 Gene Summary
This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect. [provided by RefSeq, Mar 2017]
Gene Name: MYC Binding Protein 2, E3 Ubiquitin Protein Ligase
Chromosome: CHR13: 77618791 -77901177
Locus: 13q22.3
HIPK2 Gene Summary
This gene encodes a conserved serine/threonine kinase that is a member of the homeodomain-interacting protein kinase family. The encoded protein interacts with homeodomain transcription factors and many other transcription factors such as p53, and can function as both a corepressor and a coactivator depending on the transcription factor and its subcellular localization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Name: Homeodomain Interacting Protein Kinase 2
Chromosome: CHR7: 139246315 -139477693
Locus: 7q34
Gene Diseases
The HIPK2 MYCBP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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