HIF1A-C14ORF37 Fusion FISH Probe
The HIF1A-C14ORF37 Fusion FISH Probe is used to confirm a fusion of the HIF1A and C14ORF37 genes. The fusion of the HIF1A and C14ORF37 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HIF1A-C14ORF37-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-RERE | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-REOR | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-REGO | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-REGR | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-REAQ | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-ORRE | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-OROR | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-ORGO | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-ORAQ | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-GORE | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-GOOR | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-GOGO | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-GOGR | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-GOAQ | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-GRRE | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-GROR | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-GRGO | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-GRGR | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-GRAQ | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-AQRE | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-AQOR | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-AQGO | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-AQGR | 20 (40 μL) | 200 μL |
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| HIF1A-C14ORF37-20-AQAQ | 20 (40 μL) | 200 μL |
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HIF1A Gene Summary
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
Gene Name: Hypoxia Inducible Factor 1 Alpha Subunit
Chromosome: CHR14: 62162118 -62214977
Locus: 14q23.2
C14orf37 Gene Summary
The Chromosome 14 Open Reading Frame 37 (C14orf37) gene is located on chr14 :58470807-58618847 at 14q23.1.
Gene Name: Chromosome 14 Open Reading Frame 37
Chromosome: CHR14: 58470807 -58618847
Locus: 14q23.1
Gene Diseases
The HIF1A C14ORF37 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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