HHIPL2-TLR5 Fusion FISH Probe
The HHIPL2-TLR5 Fusion FISH Probe is used to confirm a fusion of the HHIPL2 and TLR5 genes. The fusion of the HHIPL2 and TLR5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HHIPL2-TLR5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-RERE | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-REOR | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-REGO | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-REGR | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-REAQ | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-ORRE | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-OROR | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-ORGO | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-ORAQ | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-GORE | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-GOOR | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-GOGO | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-GOGR | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-GOAQ | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-GRRE | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-GROR | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-GRGO | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-GRGR | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-GRAQ | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-AQRE | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-AQOR | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-AQGO | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-AQGR | 20 (40 μL) | 200 μL |
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| HHIPL2-TLR5-20-AQAQ | 20 (40 μL) | 200 μL |
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TLR5 Gene Summary
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]
Gene Name: Toll Like Receptor 5
Chromosome: CHR1: 223282747 -223316624
Locus: 1q41
HHIPL2 Gene Summary
The HHIP Like 2 (HHIPL2) gene is located on chr1 :222695601-222721444 at 1q41.
Gene Name: HHIP Like 2
Chromosome: CHR1: 222695601 -222721444
Locus: 1q41
Gene Diseases
The HHIPL2 TLR5 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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