HEXB-FAM169A Fusion FISH Probe
The HEXB-FAM169A Fusion FISH Probe is used to confirm a fusion of the HEXB and FAM169A genes. The fusion of the HEXB and FAM169A genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HEXB-FAM169A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-RERE | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-REOR | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-REGO | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-REGR | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-REAQ | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-ORRE | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-OROR | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-ORGO | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-ORAQ | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-GORE | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-GOOR | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-GOGO | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-GOGR | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-GOAQ | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-GRRE | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-GROR | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-GRGO | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-GRGR | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-GRAQ | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-AQRE | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-AQOR | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-AQGO | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-AQGR | 20 (40 μL) | 200 μL |
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| HEXB-FAM169A-20-AQAQ | 20 (40 μL) | 200 μL |
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HEXB Gene Summary
Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Gene Name: Hexosaminidase Subunit Beta
Chromosome: CHR5: 73980968 -74017113
Locus: 5q13.3
FAM169A Gene Summary
The Family With Sequence Similarity 169 Member A (FAM169A) gene is located on chr5 :74073398-74162615 at 5q13.3.
Gene Name: Family With Sequence Similarity 169 Member A
Chromosome: CHR5: 74073398 -74162615
Locus: 5q13.3
Gene Diseases
The HEXB FAM169A Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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