HERPUD1-THADA Fusion FISH Probe
The HERPUD1-THADA Fusion FISH Probe is used to confirm a fusion of the HERPUD1 and THADA genes. The fusion of the HERPUD1 and THADA genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HERPUD1-THADA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-RERE | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-REOR | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-REGO | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-REGR | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-REAQ | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-ORRE | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-OROR | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-ORGO | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-ORAQ | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-GORE | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-GOOR | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-GOGO | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-GOGR | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-GOAQ | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-GRRE | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-GROR | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-GRGO | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-GRGR | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-GRAQ | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-AQRE | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-AQOR | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-AQGO | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-AQGR | 20 (40 μL) | 200 μL |
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| HERPUD1-THADA-20-AQAQ | 20 (40 μL) | 200 μL |
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HERPUD1 Gene Summary
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013]
Gene Name: Homocysteine Inducible ER Protein With Ubiquitin Like Domain 1
Chromosome: CHR16: 56965747 -56977793
Locus: 16q13
THADA Gene Summary
This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
Gene Name: THADA, Armadillo Repeat Containing
Chromosome: CHR2: 43457974 -43823185
Locus: 2p21
Gene Diseases
The HERPUD1 THADA Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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